Mean age was 41.9 ( SD 13.6), 79% were male, median initial Glasgow Coma Scale Score was 6.

Age, gender, initial injury severity did not significantly differ between evaluated patients and lost to follow-up, but the latter were more frequently students or unemployed. At 8-year follow-up, 261 patients were deceased, 128 were lost to follow-up, 22 refused to participate, and 86 were finally evaluated. Results: Five hundred and four patients were included between 20. Outcome was assessed with face-to-face interview 8 years after Traumatic Brain Injury, focusing on impairments, activity limitations, and participation restriction. Methods: Prospective observational study of an inception cohort of adult patients with severe traumatic brain injury in the Parisian area (PariS-TBI). However, the determinants of long-term outcome have rarely been systematically studied in a prospective longitudinal study of a homogeneous group of patients suffering exclusively from severe TBI 12Laboratoire de Psychopathologie et Neuropsychologie, EA 2027, Université Paris 8, Saint-Denis, Franceīackground and aims: Severe traumatic brain injury is a leading cause of acquired persistent disabilities, and represents an important health and economic burden.11Antenne UEROS-SAMSAH92-UGECAM IDF, Hôpital Raymond Poincaré, Garches, France.10Regional Reference Center for Bain Injury in the Parisan Area, CRFTC, Paris, France.9Laboratoire d'Imagerie Biomedicale Inserm U1146, Sorbonne Université GRC18, Paris, France.8Physical Medicine and Rehabilitation Department, APHP, Raymond-Poincaré Hospital, Garches, France.7Unité de Recherche Clinique Paris Ile-de-France Ouest, Ambroise Paré Hospital, APHP, Boulogne, France.6Physical Medicine and Rehabilitation Department, Lapeyronie Hospital, CHRU, Montpellier, France.

5Sorbonne Université GRC18, Paris, France.4Physical Medicine and Rehabilitation Department, Pitie-Salpetriere Hospital, APHP, Paris, France.3EPHE, INSERM, U1077, Neuropsychologie et Imagerie de la Mémoire Humaine, Caen, France.2Laboratoire de Recherches Cliniques et en Santé publique sur les Handicaps Psychiques, Cognitifs et Moteurs (HANDIReSP, EA4047), Université de Versailles Saint-Quentin, Montigny-Le-Bretonneux, France.1Physical Medicine and Rehabilitation Department, CHRU, Caen, France.Alexis Ruet 1,2,3 * Eléonore Bayen 4,5 Claire Jourdan 6 Idir Ghout 7 Layidé Meaude 7 Astrid Lalanne 8 Pascale Pradat-Diehl 4,9 Gaëlle Nelson 10 James Charanton 10 Philippe Aegerter 7 Claire Vallat-Azouvi 2,11,12 Philippe Azouvi 2,8

Brain injury out of work 2 years